A Case of Pancreatic Neuroendocrine Tumor presenting Iron Deficiency Anemia in a Patient with Neurofibromatosis Type 1

Author(s): Xueyu Sun, Yanan Yu, Yueping Jiang, Deming Li

Neurofibromatosis type 1 (NF1) is a dominantly inherited disease characterized by cafe´-au-lait spots in the skin and dermal neurofibromas. We report an unusual case of a 38-year-old women with NF1 presented with abdominal pain and iron deficiency anemia. Imaging studies revealed a lesion in the head of the pancreas. At surgery, a 20 mm neuroendocrine tumor was found in the head of the pancreas. We present this case of a patient with pancreatic neuroendocrine tumors (PNETs) associated with NF1 and review the literatures that have been reported to discuss the characteristics of these tumors to improve early differential.

Neurofibromatosis Type 1, Von Recklinghausen's Disease, Neuroendocrine Tumor, Pancreatic Neuroendocrine Tumor, Carcinoma, Familial Syndrome

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