Renal Cell Carcinoma and Mucinous Adenocarcinoma of Ureter after Renal Transplantation with Neoplasm of Urethra in Follow up

Author(s): Caio Eduardo Gullo, João Paulo Pretti Fantin, Luis Cesar Fava Spessoto, Marcio Gatti, José Germano F. Arruda, Thiago da Silveira Antoniassi, Pedro Francisco Ferraz de Arruda, Fernando Nestor Facio Junior

This paper presents the first case of a kidney graft recipient with double malignancy of the upper urinary system and cancer of the urethra evident four years after transplantation.

kidney tumor, ureteral tumor, urethral cancer, kidney transplant

1. Denton MD, Magee CC, Ovuworie C, Mauiyyedi S, Pascual M, Colvin RB, et al. Prevalence of renal cell carcinoma in patients with ESRD pre-transplantation: a pathologic analysis. Kidney Int. 2002;61(6):2201-2209.
2. Filocamo MT, Zanazzi M, Li Marzi V, Guidoni L, Villari D, Dattolo E, et al. Renal cell carcinoma of native kidney after renal transplantation: clinical relevance of early detection. Transplant Proc. 2009;41(10):4197-4201.
3. Kinsella SM, Coyle JP, Long EV, McWilliams SR, Maher MM, Clarkson MR, et al. Maintenance hemodialysis patients have high cumulative radiation exposure. Kidney Int. 2010;78:789-793.
4. Tsaur I, Karalis A, Probst M, Blaheta RA, Scheuermann EH, Gossmann J, et.al. Development of urological cancers in renal transplant recipients: 30-year experience at the Frankfurt Transplant Center. Cancer Sci. 2010;101(11):2430-2435.
5. Hurst FP, Jindal RM, Graham LJ, Falta EM, Elster EA, Stackhouse GB, et al. Incidence, Predictors, Costs, and Outcome of Renal Cell Carcinoma After Kidney Transplantation: USRDS Experience. Transplantation. 2010;90(8):898-904.
6. Pompeo ACL, Wroclawski EC, Sadi MV. Algoritmos em uro-oncologia. Rio de Janeiro: Elsevier, 2007.
7. Rao SN. Cancer screening in end-stage renal disease. Saudi J Kidney Dis Transpl. 2009;20:737-740.
8. Elkentaoui H, Robert G, Pasticier G, Bernhard JC, Couzi L, Merville P, et al. Therapeutic management of de novo urological malignancy in renal transplant recipients: the experience of the French Department of Urology and Kidney Transplantation from Bordeaux. Oncology. 2010;75(1):126-132.
9. Suson KD, Sausville JE, Sener A, Phelan MW. Native nephrectomy for renal cell carcinoma in transplant recipients. Transplantation. 2011;27;91(12):1376-1379.
10. Goh A, Vathsala A. Native renal cysts and dialysis duration are risk factors for renal cell carcinoma in renal transplant recipients. Am J Transpl. 2011;11:86-92.
11. Wan J, Ohl DA, Weatherbee L. Primary mucinous adenocarcinoma of renal pelvis in solitary pelvic kidney. Urology. 1993;41(3):292-294.
12. Ueda T, Okumi M, Ichimaru N, Itoh K, Matsuoka Y, Fujimoto N. Mucinous adenocarcinoma of the renal pelvis in the horseshoe kidney: a case report. Hinyokika Kiyo. 2002;48(3):187-189.
13. Shah VB, Amonkar GP, Deshpande JR, Bhalekar H. Mucinous adenocarcinoma of the renal pelvis with pseudomyxoma peritonei. Indian J Pathol Microbiol. 2008;51:536-537.
14. Kaur G, Naik VR, Rahman MNG. Mucinous adenocarcinoma of the renal pelvis associated with lithiasis and chronic gout. Singapore Med J. 2004;45(3):125-126.
15. Liwnicz BH, Lepow H, Schutte H, Fernandez R, Caberwal D. Mucinous adenocarcinoma of the renal pelvis: discussion of possible pathogenesis. J Urol. 1975;114:306-310.
16. Lutz ST, Huang DT. Combined chemoradiotherapy for locally advanced squamous cell carcinoma of the bulbomembranous urethra: a case report. J Urol. 1995;153:1616-1618.
17. Walsh PC, Retik AB. Surgery of penile and urethral carcinoma. In: Campbell´s Urology. 7th ed. WB Saunders, 1998:3395-3407.